As a major gateway of Dunhuang, the station was constructed in a cruciform symmetrical system with a distinctive Han (206 BC - 220) and Tang (618 - 907) dynasties' style.

Dunhuang Railway Station is 4.5 kilometers away from Dunhuang city, Gansu province. The station covers an area of 10,865 square meters, with 2 platforms, 8 arrival and departure lines and a receiving and dispatching capacity of 8,000 passengers.